孙海亮

孙海亮

 学科:预防兽医学
邮箱:hsun@scau.edu.cn
通讯地址:广州市天河区五山路483号华南农业大学兽医学院

个人详细情况       

    孙海亮,男,山东潍坊人,农学博士,副教授。       

    2011年毕业于华南农业大学获博士学位。2011年9月~2014年9月,在美国密西西比州立大学从事博士后工作。2014年9月~2016年6月在美国密西西比州立大学担任研究助理教授一职。2016年9月回到华南农业大学兽医学院工作,副教授。

    从事病毒学研究已有13年之久,研究热点主要集中在流感病毒的遗传演化、致病性、抗原变异、受体结合特性、气溶胶传播、跨宿主传播、病毒免疫、疫苗研发等领域,发表了17篇SCI论文,包括mBio、Journal of virology和Emerging Microbes & Infections等。

  

教育经历:

2011年6月毕业于华南农业大学兽医学院预防兽医专业,获博士学位。

2008年6月毕业于甘肃农业大学兽医学院预防兽医专业,获硕士学位。

2005年6月毕业于河南农业大学牧医工程学院动物医学专业,获学士学位。

  

工作经历:

2016年9月至今华南农业大学兽医学院首聘副教授

2014年9月~2016年6月美国密西西比州立大学兽医学院研究助理教授(Faculty)。

2011年9月至2014年9月美国密西西比州立大学兽医学院博士后 (Staff) 。


研究领域:

流感病毒的遗传演化,抗原变异,致病性、气溶胶传播,受体嗜性研究,新型疫苗研究,病毒免疫,新发传染病等

  

承担科研项目情况:     

华南农业大学启动基金20万。

  

发表论文情况

发表SCI论文17篇,其中以第一作者(或共同第一作者)发表SCI论文9 篇,单篇最高 7.3。

1. Hailiang Sun, Jialiang Yang, Tong Zhang, Li-Ping Long, Kun Jia, Guohua Yang, Richard J. Webby, Xiu-FengWan. Using sequence data to infer the antigenicity of influenza virus. M Bio. 2013 Jul 2; 4(4). pii: e00230-13. doi: 10.1128/mBio.00230-13.(影响因子7)

2. Hailiang Sun, Bryan S. Kaplan, Guihong Zhang, Jianqiang Ye, Li-Ping Long, Sherry Blackmon, Jim Cooley, Dave Smith, Ming Liao, Richard Webby, and Xiu-Feng Wan. Pathogenicity and transmission of a swine influenza A (H6N6) virus. Emerging Microbes & Infections (2017) 6, e17; doi:10.1038/emi.2017.3(影响因子5.605)

3.Hailiang Sun,  Sherry Blackmon,  Guohua Yang,  Kaitlyn Waters,  Tao Li,Ratanaporn Tangwangvivat,  Yifei Xu,  Daniel Shyu,  Feng Wen,  Jim Cooley,Lucy Senter, Xiaoxu Lin, Richard Jarman,  Larry Hanson,  Richard Webby and Xiu-Feng Wan. Zoonotic Risk, Pathogenesis, and Transmission of Avian-Origin H3N2 Canine Influenza Virus. Journal of virology, 2017 doi:10.1128/JVI.00637-17.(影响因子 4.663)

4. Hailiang Sun, Pengfei Cui, Yafen Song, Yan Qi, Xiaokang Li, Wenbao Qi , Chenggang Xu, Peirong Jiao and MingLiao. PB2 segment promotes high-pathogenicity of H5N1 avian influenza viruses in mice. Frontiers in microbiology, 2015, 6(73):1-9.(影响因子4.076)

5.Hailiang Sun,  Fred Cunningham,  Jillian Harris,  Yifei Xu,  Li-Ping Long, Katie Hanson-Dorr,  John Baroch,  Paul Fioranelli,  Mark Lutman,  Tao Li,  Kerri Pedersen,  Brandon Schmit,  Jim Cooley,  Xiaoxu Lin,  Richard Jarman,  Thomas DeLiberto, Xiu-Feng Wan. Dynamics of Virus Shedding and Antibody Responses in Influenza A Virus-Infected Feral Swine. 2015, Journal of General Virology doi:10.1099/jgv.0.000225.(影响因子3.192)

6. Hailiang Sun, Peirong Jiao, baoqin Jia, Chenggang Xu, Liangmeng Wei, Fen Shan, Kaijian Luo, Chaoan Xin, Kouxin Zhang , Ming Liao. Pathogenicity in quails and mice of H5N1 highly pathogenic avian influenza viruses isolated from ducks. Vet. microbiol, 2011, 152 : 258-265.(影响因子2.628)

7. Yifei Xu, Huabin Cao, Hongyan Liu, Hailiang Sun, Brigitte Martin, Yulong Zhao, Qi Wang, Guangfu Deng, Jianli Xue, Yibo Zong, Jing Zhu, Feng Wen, Li-Ping Long, Sook-San Wong, Nan Zhao, Xiaoshan Fu, Ming Liao, Guoliang Hu, Richard Webby, George F. Gao, and Xiu-Feng Wan. Identification of the source of An (H10N8) virus causing human infection. Infection, Genetics and Evolution, 2015(30):159–163.

并列第一作者(影响因子2.885)

8. Hailiang Sun, Peirong Jiao, Yuqiang Cheng, Runyu Yuan, Pengfei Cui, Liming Jin, Chaoan Xin and Ming Liao. The pathogenicity variation of two quail-origin H5N1 HPAV to BALB/c mice after six passages in quail. J. Anim. Vet. Adv., 2011, 10(15):1974-1980.(影响因子0.39)

9. Hailiang Sun, Jian-Li Xue, Elizabeth Bailey, Yifei Xu, Guoliang Hu, John Baroch, Yi Zhang, Lanny Pace, Thomas J. DeLiberto, and Xiu-Feng Wan. A quantitative RT-PCR assay for rapid detection of Eurasianlineage H10 subtype influenza A virus. Acta Microbiologica Sinica, 2016, 31 (5): 444.

10.Yuhua Yao, Xianhong Li, Bo Liao, Li Huang, Pingan He, Fayou Wang, Jiasheng Yang, Hailiang Sun,Yulong Zhao ,Jialiang Yang. Predicting influenza antigenicity from Hemagglutintin sequence data based on a joint random forest method. Scientific Reports 7, Article number: 1545(2017), doi:10.1038/s41598-017-01699-z.(影响因子4.259)

11. Li Huang, Xianhong Li , Pengfei Guo , Yuhua Yao , Bo Liao , Weiwei Zhang, Fayou Wang , Jiasheng Yang , Yulong Zhao , Hailiang Sun , Pingan He, Jialiang Yang. Matrix completion with side information and its applications in predicting the antigenicity of influenza viruses. Bioinformatics, 2017, Bioinformatics 33:3195-3201(影响因子7.307)

12. Brigitte Martin, Kun Jia, Hailiang Sun, Jianqiang Ye, Crystal Hall, Daphne Ware, and Xiu-Feng Wan. Detection of influenza antigenic variants directly from clinical samples using polyconal antibody based proximity ligation assays. Virology, 2015(476) 151-8.(影响因子3.2)

13. Jianqiang Ye, Yifei Xu, Jillian Harris, Hailiang Sun, Andrew S. Bowman, Fred Cunningham, Carol Cardona,Kyoungjin J. Yoon, Richard D. Slemons, Xiu-Feng Wan. Mutation from arginine to lysine at the position 189 of hemagglutinin contributes to the antigenic drift in H3N2 swine influenza viruses. Virology, 2013, 446(1-2):225-229.(影响因子3.2)

14. Jianqiang Ye, Feng Wen, Yifei Xu, Nan Zhao, Liping Long, Hailiang Sun, Jialiang Yang, Jim Cooley, G. Todd Pharr, Richard Webby, and Xiu-Feng Wan. Error-prone PCR-Based Mutagenesis Strategy for Rapidly Generating High-Yield Influenza Vaccine Candidates. Virology, 2015, 482:234-243(影响因子3.2)

15. Gu J, Zhang Y, Lian X, Sun H, Wang J, Liu W, Meng G, Li P, Zhu D, Jin Y, Cao R. Functional analysis of the interferon-stimulated response element of porcine circovirus type 2 and its role during viral replication in vitro and in vivo. Virology Journal, 2012, 9:152.(影响因子2.362)

16. Jin Cui, Nannan Qu, Yang Guo, Lan Cao, Siyu Wu, Kun Mei, Hailiang Sun, Yiliang Lu, Zhifeng Qin, Peirong Jiao, and Ming Liao. Phylogeny, Pathogenicity, and Transmission of H5N1 Avian Influenza Viruses in Chickens. Front Cell Infect Microbiol., 2017, 7:328. (影响因子4.3)

17. Brigitte E. Martin, Hailiang Sun, Margaret Carrel, Fred L. Cunningham,John A. Baroch, Katie C. Hanson-Dorr, Sean G. Young, Brandon Schmit, Jacqueline M. Nolting, Kyoung-Jin Yoon, Mark W Lutman, Kerri Pedersen, Kelly Lager, Andrew S. Bowman, Richard D. Slemons, David R. Smith,Thomas DeLiberto, Xiu-Feng Wan. US feral swine were exposed to both avian and swine influenza A viruses. AEM, 2017, doi:10.1128/AEM.01346-17AEM.01346-17.(影响因子 3.8)

  

写给学生的话:    

    态度决定高度,细节决定成败!