冯赛祥

冯赛祥

 学科:预防兽医学 
电话号码:18620564905
电子邮箱:squarefeng@126.com
通讯地址:华南农业大学兽医学院办公楼401

个人信息

    冯赛祥,男,1984年10月出生。

    本人多年从事细菌遗传及生理生化研究,主要工作是关于动物病原菌致病相关基因的功能研究。本人率先在国内建立副猪嗜血杆菌遗传操作平台,目前已鉴定多个副猪嗜血杆菌致病相关基因,其中包括表面多糖和脂质合成或代谢相关基因,为揭示该菌生理代谢与致病关系提供理论基础。研究成果以第一作者或并列第一作者公开发表学术论文6篇,所建立的遗传改造技术已申报专利并用于基因工程疫苗开发及应用。  

  

工作经历:

2017.10-至今,华南农业大学兽医学院预防兽医系,讲师

 

教育背景:

2014.11-2017.03  华南农业大学预防兽医学  博士后

2013.08-2014.05  Virginia Tech           访问学者

2010.09-2014.06  华南农业大学            博士

2007.09-2010.06  华南农业大学            硕士

2003.09-2007.06  华南农业大学            学士

 

研究方向:

1、动物病原细菌生理生化及遗传研究。

2、动物病原细菌多糖及脂质合成代谢研究。

3、动物病原细菌遗传工程疫苗开发与应用。

 

部分已发表的科研论文:

1.S. Feng, C. Xu, K. Yang, H. Wang, H. Fan, M. Liao: Either fadD1 or fadD2 gene, encoding acyl-CoA synthetase, is essential for survival of Haemophilus parasuis SC096. Front Cell Infect Microbiol (2017)

2.S. Feng, L. Xu, C. Xu, H. Fan, M. Liao and T. Ren: Role of acrAB in antibiotic resistance of Haemophilus parasuis serovar 4. Vet. J., 202(1), 191-4 (2014)

3.S. X. Feng, J. C. Ma, J. Yang, Z. Hu, L. Zhu, H. K. Bi, Y. R. Sun and H. H. Wang: Ralstonia solanacearum fatty acid composition is determined by interaction of two 3-ketoacyl-acyl carrier protein reductases encoded on separate replicons. BMC Microbiol., 15, 223 (2015)

4.Q. Zhou, S. Feng (co-firstauthor), J. Zhang, A. Jia, K. Yang, K. Xing, M. Liao and H. Fan: Two Glycosyltransferase Genes of Haemophilus parasuis SC096 Implicated in Lipooligosaccharide Biosynthesis, Serum Resistance, Adherence, and Invasion. Front Cell Infect Microbiol, 6, 100 (2016)

5.Y. Zou, S. Feng (co-firstauthor), C. Xu, B. Zhang, S. Zhou, L. Zhang, X. He, J. Li, Z. Yang and M. Liao: The role of galU and galE of Haemophilus parasuis SC096 in serum resistance and biofilm formation. Vet. Microbiol., 162(1), 278-84 (2013)

6.B. Zhang, S. Feng (co-firstauthor), C. Xu, S. Zhou, Y. He, L. Zhang, J. Zhang, L. Guo and M. Liao: Serum resistance in Haemophilus parasuis SC096 strain requires outer membrane protein P2 expression. FEMS Microbiol. Lett., 326(2), 109-15 (2012)

7.M. Dai, S. Wu, M. Feng, S. Feng, C. Sun, D. Bai, M. Gu, M. Liao and W. Cao: Recombinant chicken interferon-alpha inhibits the replication of exogenous avian leukosis virus (ALV) in DF-1 cells. Mol. Immunol., 76, 62-9 (2016)

8.C. Xu, L. Zhang, B. Zhang, S. Feng, S. Zhou, J. Li, Y. Zou and M. Liao: Involvement of lipooligosaccharide heptose residues of Haemophilus parasuis SC096 strain in serum resistance, adhesion and invasion. Vet. J., 195(2), 200-4 (2013)

9.B. Zhang, Y. He, C. Xu, L. Xu, S. Feng, M. Liao and T. Ren: Cytolethal distending toxin (CDT) of the Haemophilus parasuis SC096 strain contributes to serum resistance and adherence to and invasion of PK-15 and PUVEC cells. Vet. Microbiol., 157(1-2), 237-42 (2012)

10.B. Zhang, C. Xu, S. Zhou, S. Feng, L. Zhang, Y. He and M. Liao: Comparative proteomic analysis of a Haemophilus parasuis SC096 mutant deficient in the outer membrane protein P5. Microb Pathog, 52(2), 117-24 (2012)

11.S. Zhou, X. He, C. Xu, B. Zhang, S. Feng, Y. Zou, J. Li and M. Liao: The outer membrane protein P2 (OmpP2) of Haemophilus parasuis induces proinflammatory cytokine mRNA expression in porcine alveolar macrophages. Vet. J., 199(3), 461-4 (2014)

12.B. Zhang, C. Xu, L. Zhang, S. Zhou, S. Feng, Y. He and M. Liao: Enhanced adherence to and invasion of PUVEC and PK-15 cells due to the overexpression of RfaD, ThyA and Mip in the ΔompP2 mutant of Haemophilus parasuis SC096 strain. Vet. Microbiol., 162(2-4), 713-23 (2013)

13.L. Zhu, J. Cheng, B. Luo, S. Feng, J. Lin, S. Wang, J. E. Cronan and H. Wang: Functions of the Clostridium acetobutylicium FabF and FabZ proteins in unsaturated fatty acid biosynthesis. BMC Microbiol., 9, 119 (2009)