来源:兽医学院 发布时间:2025-06-23 浏览次数:6713

简介

 

         曾东平,男,广东揭西人,1979年10月出生,正高级实验师,博士,基础兽医学(兽医药理与毒理学方向)、兽医药学和兽医硕士导师,现任兽医学院实验教学中心主任。2002年华南农业大学兽医专业本科毕业,2005年华南农业大学获基础兽医学硕士学位并留校任教,2012年华南农业大学基础兽医学专业获博士学位,2024年晋升为正高级实验师。二十多年来,一直从事兽医药理学的教学科研工作。在兽药研究与安全评价开展了系列研究工作,发表论文近30篇,SCI论文20篇,以第一作者发表SCI 4篇,参与申报专利7项(授权4项),参编著作3部。


学历


(1) 2008-09 至 2012-12, 华南农业大学, 基础兽医学, 博士

(2) 2002-09 至 2005-07, 华南农业大学, 基础兽医学, 硕士

(3) 1998-09 至 2002-07, 华南农业大学, 兽医, 学士


工作经历


(1) 2024-07 至 今, 华南农业大学, 兽医学院, 正高级实验师

(2) 2016-10 至 2017-10, 美国堪萨斯州立大学, 兽医学院, 访问学者

(3) 2012-12 至 2024-07, 华南农业大学, 兽医学院, 高级实验师

(4) 2008-07 至 2012-12, 华南农业大学, 兽医学院, 实验师

(5) 2005-07 至 2008-07, 华南农业大学, 兽医学院, 助理实验师


研究领域


兽药研究与安全评价


承担科研项目情况


(1) 农业农村部,国家重点研究计划重点专项子课题,抗隐孢子虫新药物靶标的筛选与验证,2022-01至2027-12,50万元,在研,主持

(2) 企业委托,横向合作项目,伊曲康唑内服溶液对猫癣的临床疗效验证试验,2024-10至2026-12,78万元,在研,主持

(3) 企业委托,横向合作项目,米尔贝肟吡喹酮片在猫体内的生物等效性试验,2024-01至2025-12,180万元,在研,主持

(4) 企业委托,横向合作项目,阿莫西林克拉维酸钾片在犬体内的生物等效性试验,2023-06至2025-12,95万元,在研,主持


代表论著(*通讯作者)

      

         (1) Ma Minglang, Zhang Yongxiang, Fang Yanjun, Lu Yixing, Huang Huiguo, Zeng Zhenling, Zeng Dongping. Pharmacokinetics and tissue distribution of LN002, a new compound alternative oxidase inhibitor against Cryptosporidium in rats. Frontiers in Pharmacology, 2024, 15: 1413872.

        (2) Zhang Wanyin, Lu Yixing, Ma Minglang, Yang Jinyu, Huang Huiguo, Peng Xianfeng, Zeng Zhenling, Zeng Dongping. Ex vivo pharmacokinetic/pharmacodynamic of hexahydrocolupulone against Clostridium perfringens in broiler chickens. Frontiers in Veterinary Science, 2024, 11: 1362292.

        (3) Zhang Yongxiang, Ma Minglang, Yang Jinyu, Qiu Xiaotong, Xin Lin, Lu Yixing, Huang Huiguo, Zeng Zhenling, Zeng Dongping. Preparation, Characterization, and Oral Bioavailability of Solid Dispersions of Cryptosporidium parvum Alternative Oxidase Inhibitors. International Journal of Molecular Sciences, 2024, 25 (13): 25137025

        (4) Lu Yixing, Di Wang, Zhang Yongxiang, Hu Yueying, Lu Jiaxuan, Zeng Zhenling, Zeng Dongping. Preparation and Antimicrobial Activity of a Film-Forming Polyhexamethylene Biguanide Teat Disinfectant. International Journal of Molecular Sciences, 2023, 24: 17444.

        (5) Xie Shiting, Lu Yixing, Wang Jun, Lin Changcheng, Ye Peiyu, Liu Xiaolin, Xiong Wenguang, Zeng Zhenling, Zeng Dongping. Development and validation of an LC–MS/MS method for the simultaneous quantification of milbemycin oxime and praziquantel in plasma: application to a pharmacokinetic study in cats. Frontiers in Veterinary Science, 2023, 10: 1285932.

        (6) Lu Yixing, Zhang Wanying, Zhang Yongxiang, Wu Sujuan, Ma Minglang, Peng Xianfeng, Zeng Zhenling, Zeng Dongping. Metabolite Identification of Isopropoxy Benzene Guanidine in Rat Liver Microsomes by Using UHPLC-Q-TOF-MS/MS. International Journal of Molecular Sciences,2023, 24(8): 7313.

        (7) Huang Honghao, Lu Yixing, Wu Sujuan, Ma Zhenbao, Zeng Dongping, Zeng Zhenling.Identification of blaIMI-mediated carbapenem-resistant Enterobacter from a duck farm in China. Journal of Integrative Agriculture, 2023, 22(8): 2500-2508.

        (8) 张永祥, 胡健欣, 陆毅兴, 胡悦莹, 卢嘉璇, 辛琳, 曾振灵, 曾东平.广东省某屠宰场猪源肠球菌的分离鉴定及耐药性和毒力基因分析.中国畜牧兽医, 2023, 50(11):4714-4723.

        (9) Lu Yixing, Yang Liuye, Zhang Wanying, Xie Shiting, Zhao Feifei, Peng Xianfeng, Qin Zonghua, Zeng Dongping, Zeng Zhenling. Enhancement of the oral bioavailability of isopropoxy benzene guanidine though complexation with hydroxypropyl-β-cyclodextrin. Drug Delivery, 2022, 29(1): 2824-2830.

        (10) Lu Yixing, Yang Liuye, Zhang Wanying, Li Jie, Peng Xianfeng, Qin Zonghua, Zeng Zhenling, Zeng Dongping. Pharmacokinetics and pharmacodynamics of isopropoxy benzene guanidine against Clostridium perfringens in an intestinal infection model. Frontiers in Veterinary Science, 2022, 9: 1004248.

        (11) Kong Lingli, Lu Yixing, Yang Liuye, Zhang Wanying, Zuo Beini, Peng Xianfeng, Qin Zonghua, Li Miao, Zeng Zhenling, Zeng Dongping. Pharmacokinetics and Pharmacodynamics of Colistin Combined With Isopropoxy Benzene Guanidine Against mcr-1-Positive Salmonella in an Intestinal Infection Model. Frontiers in Microbiology, 2022, 13: 907116.

        (12) 孔伶俐, 林翠萍, 陆毅兴, 姚雪军, 劳华杰, 曾东平. 牛奶中多西环素残留消除及最大残留限量. 中国兽医学报, 2022, 42(04): 750-755.

        (13) 王波, 曾艺元, 邬嘉豪, 沈祥广, 贺利民, 曾振灵, 曾东平. 酮洛芬注射液在乳牛体内的残留消除研究. 中国兽医科学, 2020, 50(02): 240-246.

        (14) Zeng Dongping, Sun Meizhen, Lin Zhoumeng, Li Miao, Gehring Ronette, Zeng Zhenling, Pharmacokinetics and Pharmacodynamics of Tildipirosin Against Pasteurella multocida in a Murine Lung Infection Model. Frontiers in Microbiology, 2018, 9: 1038.

        (15) Zeng Dongping, Lin Zhoumeng, Zeng Zhenling, Fang Binghu, Li Miao, Cheng Yi-Hsien, Sun Yongxue. Assessing Global Human Exposure to T-2 Toxin via Poultry Meat Consumption Using a Lifetime Physiologically Based Pharmacokinetic Model. Journal of Agricultural and Food Chemistry, 2019, 67(5): 1563-1571.

        (16) Zeng Dongping, Lin Zhoumeng, Fang Binghu, Li Miao, Gehring Ronette, Riviere Jim E., Zeng Zhenling. Pharmacokinetics of Mequindox and Its Marker Residue 1,4-Bisdesoxymequindox in Swine Following Multiple Oral Gavage and Intramuscular Administration: An Experimental Study Coupled with Population Physiologically Based Pharmacokinetic Modeling. Journal of Agricultural and Food Chemistry, 2017, 65(28): 5768-5777.