熊文广

熊文广

 学科:基础兽医学        
电子邮件:xiongwg@scau.edu.cn
通讯地址:广州市天河区五山路483号 华南农业大学兽医学院 510642

个人详细情况

熊文广,男,农学博士,副教授。从事动物源细菌耐药性和兽药研制与安全性评价的研究,在肠道细菌耐药基因组学和新型抗菌剂如噬菌体研发等方面已开展系列工作。主持多个国家级和省部级项目,在《Microbiome》等期刊发表学术论文20余篇。

学历及培训经历:

2012年9月-2016年7月  华南农业大学/香港大学  联合培养博士研究生

2009年9月-2012年7月  华南农业大学  硕士研究生

2005年9月-2009年7月  西南科技大学  本科生 

工作经历:

20167至今  华南农业大学副教授 

研究领域:

·细菌对抗菌药的耐药机制

·兽药研制与安全性评价

承担科研项目情况:

·国家自然科学基金青年基金项目,通过宏基因组学研究影响抗生素耐药基因在肉鸡肠道菌群中持久存在的关键因素;

·广东省自然科学基金面上项目,应用噬菌体递呈CRISPR-Cas9系统逆转MRSA耐药性的研究;

·广州市科技计划项目,基于CRISPR/Cas9的新型抗菌剂杀灭鸭疫里默氏杆菌的应用基础研究;

·技术服务课题,兽药临床前和临床试验研究。

 

代表论著:(*通讯作者)

(1) Jiaxiong Zeng, Yu Pan, JintaoYang, Mengtian Hou, Zhenling Zeng*, Wenguang Xiong*, Metagenomic insights into the distribution of antibiotic resistome between the gut-associated environments and the pristine environments, Environment International, 2019, 126:346~354.

(2) Wenguang Xiong, Yulin Wang, Yongxue Sun, Liping Ma, Qinglin Zeng, Xiaotao Jiang, Andong Li, Zhenling Zeng*, Tong Zhang*, Antibiotic-mediated Changes in the Faecal Microbiome of Broiler Chickens Defines the Incidence of Antibiotic Resistance Genes, Microbiome, 2018, 6:34.

(3) Wenguang Xiong, Mei Wang, Jinjun Dai, Yongxue Sun*, Zhenling Zeng*, Application of Manure Containing Tetracyclines Slowed Down the Dissipation of Tet Resistance Genes and Caused Changes in the Composition of Soil Bacteria, Ecotoxicology and Environmental Safety, 2018, 147: 455~60.

(4) Wenguang Xiong#, Yongxue Sun#, Tong Zhang, Xueyao Ding, Yafei Li, Mianzhi Wang, Zhenling Zeng*, Antibiotics, Antibiotic Resistance Genes, and Bacterial Community Composition in Fresh Water Aquaculture Environment in China, Microbial Ecology, 2015, 70(2): 425~432.

(5) Wenguang Xiong#, Yongxue Sun#, Xueyao Ding, Mianzhi Wang, Zhenling Zeng*, Selective pressure of antibiotics on ARGs and bacterial communities in manure-polluted freshwater-sediment microcosms, Frontiers in Microbiology, 2015, 6.

(6) Wenguang Xiong, Yongxue Sun, Xueyao Ding, Yiming Zhang, Xiaoxia Zhong, Wenfei Liang, Zhenling Zeng*, Responses of plasmid-mediated quinolone resistance genes and bacterial taxa to (fluoro)quinolones-containing manure in arable soil, Chemosphere, 2015, 119: 473~478.

(7) Wenguang Xiong, Zhenling Zeng*, Yiming Zhang, Xueyao Ding, Yongxue Sun*, Fate of metal resistance genes in arable soil after manure application in a microcosm study, Ecotoxicology and Environmental Safety, 2015, 113: 59~63. 

写给学生的话:

祝愿大家学业进步、学有所成