Na Li

Na Li

 Discipline:	Preventive Veterinary Medicine
E-Mail:	nli@scau.edu.cn
Address:	College of Veterinary Medicine, South China Agricultural University, 510642
Additional Information:	Department of Veterinary Parasitology  

Resume:

Na Li, Female, Born in May 2nd, 1981, Henan Province, Ph.D. in Biomedical Engineering, Associate Professor.

She received her Ph.D. Degree at Tongji University in 2011. Followed by two years of postdoctoral fellow at Centers for Disease Control and Prevention, USA. She received the lecturer position at East China University of Science and Technology in 2013, and received the associate professor position at South China Agricultural University in 2017. 

Na Li has been doing her research for more than ten years on pathogen biology, molecular biology, and population genetics of zoonotic parasites including Cryptosporidium, Giardia, Cyclospora, and microsporidia. Her research is currently focusing on genetic determinants for host adaption, pathogenic mechanisms associated with virulence, and molecular targets for drugs and vaccines. She has published 32 SCI papers, including Emerg Infect Dis (two first-author papers), PLoS Neglect Trop Dis, BMC Genomics, Parasite Vector, J Clin Microbiol, etc., which have totally been cited for more than 300 times. She has presented her work in academic conferences for more than 10 times.

Education and Training Program: 

Jan 2011 – Oct 2012: Post-doctoral fellow, Division of Foodborne, Waterborne, and Environmental Diseases, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA

Jan 2008 – Dec 2010: Guest researcher, Division of Foodborne, Waterborne, and Environmental Diseases, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA

Mar 2007 – Jan 2011: Ph.D., Biomedical Engineering, School of Life Sciences and Technology, Tongji University, Shanghai, China

Sep 2003 – Jun 2006: M.S., Biophysics, School of Physical Engineering, Zhengzhou University, Zhengzhou, China

Sep 1999 – Jun 2003: B.S., Biotechnology, College of Life Sciences, Henan Normal University, Xinxiang, China

Working Experience: 

Apr 2017 – present: Associate Professor, Department of Veterinary Parasitology, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China 

Mar 2013 – Feb 2017: Lecturer, School of Resources and Environmental Engineering, East China University of Science and Technology, Shanghai, China 

Research Interests:

Genetic determinants for host adaption

Pathogenic mechanisms associated with virulence and invasion

Molecular targets for drugs and vaccines

Molecular diagnosis and source tracking

Grants: 

1.National Key R&D Program of China (12/2017-12/2021) (Project No. 2017YFC1601200). Rapid detection technology and equipment development for important foodborne parasites. RMB 350, 000.

2.Start Funding. South China Agricultural University. RMB 300, 000.

3.National Natural Science Foundation of China (01/2014-12/2016) (Project No. 31302078). Intra-species host adaptation and geographical segregation in Cryptosporidium ubiquitum. RMB 220, 000.

4.Open Funding Project of the State Key Laboratory of Veterinary Etiological Biology (09/2014-08/2016) (Project No. SKLVEB2014KFKT008). The development of an innovative method for Cryptosporidium ubiquitum source tracking with high resolution. RMB 120,000.

5.Fundamental Research Funds for the Central Universities (06/2013-05/2015) (Project No. WB1314053). The transmission mechanism of zoonotic pathogen Cryptosporidium ubiquitum between humans, animals and environment. RMB 120, 000.

Publications:

1.Guo, Y., Li, N., Ortega, Y., Zhang, L., Roellig, D. M., Feng, Y.*, Xiao, L. (2018) Population genetic characterization of Cyclospora cayetanensis from discrete geographical regions. Experimental Parasitology. 184: 121-127.

2.Li, B., Wu, H., Li, N., Su, J., Jia, R., Jiang, J., Feng, Y., Xiao, L. (2017) Preliminary characterization of MEDLE-2, a protein potentially involved in the invasion of Cryptosporidium parvum. Frontiers in Microbiology. 8:1647.

3.Feng, Y., Li, N., Roellig, D.M., Kelley, A., Liu, G., Amer, S., Tang, K., Zhang, L., Xiao, L. (2017) Comparative genomic analysis of the IId subtype family of Cryptosporidium parvum. International Journal for Parasitology. 47: 281-290 

4.Liu, S., Roellig, D. M., Guo, Y., Li, N., Frace, M. A., Tang, K., Zhang, L., Feng, Y.*, Xiao, L.* (2016) Evolution of mitosome metabolism and invasion-related proteins in Cryptosporidium. BMC Genomics. 17: 1006.

5.Tang, Y.†, Li, N. †, Song, M., Roellig, D. M., Feng, Y., Xiao, L.* (2016) Development of a multilocus sequence typing tool for high-resolution subtyping and genetic structure characterization of Cryptosporidium ubiquitum. Infection Genetics and Evolution. 45: 256-261.

6.Feng, L., Liu, S., Wu, W., Ma, J., Li, P., Xu, H., Li, N.*, Feng, Y. (2016) Dominant genera of cyanobacteria in Lake Taihu and their relationships with environmental factors. Journal of Microbiology. 54: 468-476.

7.Guo, Y., Roellig, D. M., Li, N., Tang, K., Frace, M., Ortega, Y., Arrowood, M. J., Feng, Y., Qvarnstrom, Y., Wang, L., Moss, D. M., Zhang, L., Xiao, L. (2016) Multilocus sequence typing tool for Cyclospora cayetanensis. Emerging Infectious Diseases. 22: 1464-1467.

8.Xu, H., Jin, Y., Wu, W., Li, P., Wang, L., Li, N.*, Feng, Y.*, Xiao, L. (2016) Genotypes of Cryptosporidium spp., Enterocytozoon bieneusi and Giardia duodenalis in dogs and cats in Shanghai, China. Parasites & Vectors. 9: 121.

9.Li, N., Neumann, N. F., Ruecker, N., Alderisio, K. A., Sturbaum, G. D., Villegas, E. N., Chalmers, R., Monis, P., Feng, Y.Y., Xiao, L.* (2015) Development and evaluation of three real-time PCR assays for genotyping and source tracking Cryptosporidium in water. Applied and Environmental Microbiology. 81: 5845-5854.

10.Guo, Y. Q., Tang, K., Rowe, L., Li, N., Roellig, D. M., Knipe, K., Frace, M., Yang, C. F., Feng, Y.*, Xiao, L.* (2015) Comparative genomic analysis reveals occurrence of genetic recombination in virulent Cryptosporidium hominis subtypes and telomeric gene duplications in Cryptosporidium parvum. BMC Genomics. 16: 320.

11.Li, N., Ye, J. B., Arrowood, M. J., Ma, J. B., Wang, L, Xu, H. L., Feng Y.*, Xiao, L. (2015) Identification and morphologic and molecular characterization of Cyclospora macacae n. sp. from rhesus monkeys in China. Parasitology Research. 114: 1811-1816.

12.Guo, Y. Q., Li, N., Lyseen, C., Frace, M., Tang, K., Sammons, S., Roellig, D., Feng, Y.*, Xiao, L.* (2015) Isolation and enrichment of Cryptosporidium DNA and verification of DNA purity for whole genome sequencing. Journal of Clinical Microbiology. 53: 641-647.

13.Li, N., Xiao, L., Alderisio, K., Elwin, K., Cebelinski, E., Chalmers, R., Santin, M., Fayer, R., Kvac, M., Ryan, U., Sak, B., Stanko, M., Guo, Y. Q., Wang, L., Zhang, L. X., Cai, J. Z., Roellig , D., Feng, Y.* (2014) Subtyping Cryptosporidium ubiquitum, a zoonotic pathogen emerging in humans. Emerging Infectious Diseases. 20: 217-224.

14.Feng, Y.*, Tiao, N., Li N., Hlavsa, M., Xiao, L.* (2014) Multilocus sequence typing of an emerging Cryptosporidium hominis subtype in the United States. Journal of Clinical Microbiology. 52: 524-530.

15.Feng, Y.*, Torres E., Li N., Wang L., Bowman, D., Xiao, L. (2013) Population genetic characterization of dominant Cryptosporidium parvum subtype IIaA15G2R1. International Journal for Parasitology. 43: 1141-1147.

16.Li, N., Xiao, L., Cama, V., Ortega, Y., Gilman, R. H., Guo, M., Feng, Y.* (2013) Genetic recombination and Cryptosporidium hominis virulent subtype IbA10G2. Emerging Infectious Diseases. 19: 1573-1582.

17.Li, N., Xiao, L., Wang, L., Zhao, S. M., Zhao, X. K., Duan, L. P., Guo, M. J., Liu, L. L., Feng, Y.* (2012) Molecular surveillance of Cryptosporidium spp., Giardia duodenalis, and Enterocytozoon bieneusi by genotyping and subtyping parasites in wastewater. PLoS Neglected Tropical Diseases. 6: e1809.

18.Feng, Y.*, Li, N., Dearen, T., Lobo, M. L., Matos, O., Cama, V., Xiao, L.* (2011) Development of a multilocus sequence typing tool for high resolution genotyping of Enterocytozoon bienuesi. Applied and Environmental Microbiology. 77: 4822-4828.

To Students:

  Nothing is impossible to a willing heart.